Nexgard vs. Simparica: Select the Best Flea and Tick Treatment for Your Dog

Choosing the right flea and tick treatment is a challenge many dog parents face due to the myriad of options in the market. If you find yourself in front of the same dilemma, we’re here to help you with solid suggestions. Nexgard and Simparica are two names that often pop up in conversations among pet parents and veterinarians alike.
These powerful treatments are highly effective when it comes to protecting dogs against fleas and ticks. But how do they measure up against each other, and which one is ideal for your dog? We’ll find out in this side-by-side comparison, navigating the essential insights of Nexgard chewables and Simparica chewables. Furthermore, we’ve included a selection guide to help you make an informed decision.
So make sure you read till the end!
Nexgard vs. Simparica: Exploring the Fundamentals
This segment will provide a closer look at the effectiveness and coverage of both these treatments.
Nexgard Chewables
Nexgard Chewable is a beef-flavored oral flea and tick treatment for dogs featuring Afoxolaner as the active ingredient. This easy-to-administer monthly treatment protects dogs against fleas and ticks and is indicated for the prevention of Lyme disease.
Let’s understand it better with the product specifications of Nexgard for Dogs:
- Highly palatable beef-flavored chews.
- Kills fleas before they can lay eggs.
- Treats and controls a range of tick infestations, including black-legged ticks, American dog ticks, lone star ticks, brown dog ticks, and long-horned ticks.
- Indicated to prevent Lyme disease.
- Starts killing fleas after 4 hours of administration.
- Recommended for dogs and puppies from 8 weeks of age, weighing at least 4 lbs.
Simparica Chewables
Simparica Chewables is a highly praised and preferred oral treatment for protection against external parasites in dogs. These flavored chewable tablets contain Sarolaner as the active ingredient and are indicated to protect dogs against fleas and ticks. Plus, it is recommended to prevent Lyme disease infections.
Also, Read: Understanding Lyme Disease In Dogs
Let’s discuss the features of Simparica Chewables for dogs:
- Easy to administer chewable tablets.
- Indicated for the treatment and prevention of flea infestations.
- Treats and controls tick infestations caused by lone star ticks, Gulf Coast ticks, American dog ticks, black-legged ticks, brown dog ticks, and Asian long-horned ticks.
- Recommended to prevent Lyme disease by killing black-legged ticks.
- Begins killing fleas within 3 hours of administration.
- Recommended for puppies and dogs from 6 months of age, weighing at least 2.8 lbs
Nexgard vs. Simparica: Side-by-Side Comparison
Let’s check out the differences and similarities between Nexgard Chewables and Simparica Chewables with the following comparison table.

Selection Guide
By now, the comparison table and features must have made it apparent that Nexgard and Simparica are quite similar in their effectiveness and coverage. However, there are peculiar differences that will impact the final decision. So, to answer the question of which one to select, you need to focus on the following observations:
- Both Nexgard Chewables and Simparica Chewables are effective for the treatment and prevention of flea infestations.
- Simparica is slightly ahead in terms of efficacy as it starts killing fleas within 3 hours of administration. On the other hand, Nexgard begins killing them within 4 hours of administration.
- Simparica Chewables covers 6 tick species in total, whereas Nexgard Chewables covers 5 tick species. Simparica covers Gulf Coast ticks which Nexgard does not.
- Both treatments are recommended for the prevention of Lyme disease in dogs.
- Nexgard Chewables is suitable for dogs and puppies from 8 weeks of age, weighing at least 4 lbs. On the other hand, Simparica Chewable is recommended for dogs from 6 months of age, weighing at least 2.8 lbs.
Read More- 7 Ways to Protect Pets from Fleas and Ticks
Conclusion
Keep in mind the observations shared in the selection guide to make an informed decision. However, it’s best to consult your vet before taking the final call. They will provide a suggestion best suited for your dog based on their condition and medical history.
The post Nexgard vs. Simparica: Select the Best Flea and Tick Treatment for Your Dog appeared first on DiscountPetMart.
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